GSE247880 DNA methylation alterations across time and space in paediatric brain tumours

Contributors : Anna Wenger ; Sandra Ferreyra Vega ; Helena Car énSeries Type : Methylation profiling by genome tiling arrayOrganism :DNA methylation is increasingly used for tumour classification and has expanded upon the> 100 currently known brain tumour entities. A correct diagnosis is the basis for suitable treatment for patients with brain tumours, which is the leading cause of cancer-related death in children. DNA methylation profiling is required for diagnosis of certain tumours, and used clinically for paediatric brain tumours in several countries. We therefore evaluated if the methylation-based classification is robust in different locations of the same tumour, and determined how the methylation pattern changed over time to relapse.
Source: GEO: Gene Expression Omnibus - Category: Genetics & Stem Cells Tags: Methylation profiling by genome tiling array Source Type: research