Performance of the IMPACT and CRASH prognostic models for traumatic brain injury in a contemporary multicenter cohort: a TRACK-TBI study

CONCLUSIONS: The IMPACT and CRASH models adequately discriminated mortality and unfavorable outcome. Observed overestimations of mortality and unfavorable outcome underscore the need to update prognostic models to incorporate contemporary changes in TBI management and case-mix. Investigations to elucidate the relationships between increased survival, outcome, treatment intensity, and site-specific practices will be relevant to improve models in specific TBI subpopulations (e.g., older adults), which may benefit from the inclusion of blood-based biomarkers, neuroimaging features, and treatment data.PMID:38489823 | DOI:10.3171/2023.11.JNS231425

Source: Journal of Neurosurgery - March 15, 2024 Category: Neurosurgery Authors: John K Yue Young M Lee Xiaoying Sun Thomas A van Essen Mahmoud M Elguindy Patrick J Belton Dana Pisic ă Ana Mikolic Hansen Deng John H Kanter Michael A McCrea Yelena G Bodien Gabriela G Satris Justin C Wong Vardhaan S Ambati Ramesh Grandhi Ava M Puccio P Source Type: research