Does blocking the renin-angiotensin system mitigate acute kidney injury following heart transplantation?

Over the past decades, advancements in immunosuppressive therapy, organ preservation, surgical techniques and postoperative care have led to improved long term survival after heart transplantation.1,2 Despite these advances, acute kidney injury (AKI) after cardiac transplantation remains a common complication associated with increased morbidity and mortality.3 Heart transplant recipients are at increased risk of AKI because of pre-existing chronic kidney disease (CKD), often attributed to prolonged low cardiac output state or cardiorenal syndrome.
Source: Journal of Cardiothoracic and Vascular Anesthesia - Category: Anesthesiology Authors: Tags: Editorial Source Type: research