Pharmacokinetics of polymyxin B in different populations: a systematic review

CONCLUSION: We conclude that small sample sizes, lack of multicentre collaboration, and patient homogeneity are the primary reasons for the discrepancies in the results of the current studies. In addition, most of the studies limited in the internal evaluation, which confined the implementation of model-informed precision dosing strategies.PMID:38483544 | DOI:10.1007/s00228-024-03666-w

Source: Clinical Lung Cancer - March 14, 2024 Category: Cancer & Oncology Authors: Xing Wang Wenqiang Xiong Maolian Zhong Yan Liu Yuqing Xiong Xiaoyi Yi Xiaosong Wang Hong Zhang Source Type: research