Exosome-transmitted podoplanin promotes tumor-associated macrophage-mediated immune tolerance in glioblastoma

CONCLUSIONS: This investigation underscores that EVsPDPN derived from glioblastoma cells contributes to M2 macrophage-mediated immunosuppression and is a potential prognostic marker and therapeutic target in glioblastoma.PMID:38470096 | DOI:10.1111/cns.14643

Source: CNS Neuroscience and Therapeutics - March 12, 2024 Category: Neuroscience Authors: Mengwan Wu Ying Shi Yuyang Liu Hongxiang Huang Jiajia Che Jing Shi Chuan Xu Source Type: research