Pharmacokinetics of polymyxin B in different populations: a systematic review

ConclusionWe conclude  that small sample sizes, lack of multicentre collaboration, and patient homogeneity are the primary reasons for the discrepancies in the results of the current studies. In addition, most of the studies limited in the internal evaluation, which confined the implementation of model-informed precis ion dosing strategies.
Source: European Journal of Clinical Pharmacology - Category: Drugs & Pharmacology Source Type: research