ESTRO-SIOPE guideline: Clinical management of radiotherapy in atypical teratoid/rhabdoid tumors (AT/RTs)

Atypical teratoid/rhabdoid tumors (AT/RT) are tumors of the central nervous system (CNS) most commonly diagnosed in very young children [1 –5], with most (70–80 %) tumors found in children under three years of age [6,7]. The German Childhood Cancer Registry reported that the median age at diagnoses was 18 months [8]. These rare embryonal tumors are locally aggressive and one of the most malignant CNS tumors. Also, they spread t hroughout the CNS by cerebrospinal fluid (CSF). Up to one-third of the patients have disseminated disease in the brain or spinal canal or both at diagnosis [9,10].

Source: Radiotherapy and Oncology - March 13, 2024 Category: Radiology Authors: Beate Timmermann, Claire Alapetite, Karin Dieckmann, Rolf-Dieter Kortmann, Yasmin Lassen-Ramshad, John H. Maduro, Monica Ramos Albiac, Umberto Ricardi, Damien C. Weber Tags: Original Article Source Type: research