Tumor Tissue Modified Viral HPV DNA Monitoring in Patients with Recurrent, Metastatic HPV-driven Oropharyngeal Cancer

Monitoring circulating tumor tissue modified viral (TTMV)-HPV DNA during post-treatment surveillance is a tool for detecting recurrence in patients with HPV-positive oropharyngeal squamous cell carcinoma (OPSCC). We investigated the utility of the assay to capture therapeutic response and predict survival outcomes in patients with recurrent, incurable or metastatic (R/M) disease.

Source: International Journal of Radiation Oncology * Biology * Physics - March 14, 2024 Category: Radiology Authors: G.J. Hanna, J.N. Lukens, J. Jabalee, E.M. Rettig, M. Posner, K. Misiukiewicz, E. Genden, L. Sun, Z. Belal, E. MacDuffie, S. Roof Tags: 152 Source Type: research