Hypofractionated Radiotherapy for Merkel Cell Carcinoma

Merkel cell carcinoma (MCC) is a radiosensitive skin cancer. Historically, radiation treatment for MCC has involved standard 1.8-2 Gy fractions treated daily over 4-6 weeks. For other cutaneous malignancies, radiation treatment with daily doses>2 Gy has increased in prevalence in order to reduce treatment time and increase patient convenience. The equivalence of such hypofractionated treatment regimens to standard fractionation regimens for tumor control and skin toxicity has been shown for common cutaneous malignancies such as basal cell and squamous cell carcinomas.
Source: International Journal of Radiation Oncology * Biology * Physics - Category: Radiology Authors: Tags: 251 Source Type: research