Effect of Honokiol on culture time and survival of Alzheimer's disease iPSC-derived neurons

CONCLUSION: AD iPSC-derived neurons had a high viability rate when cultured in the presence of honokiol. These results have shown that AD iPSC-derived neurons can be an excellent model for screening neurotrophic agents and improving the conditions for long-term cultures of human iPSC-derived neurons. Honokiol proves to be a potential candidate for cellular therapeutics against neurodegenerative disorders.PMID:38327632 | PMC:PMC10844589 | DOI:10.34172/bi.2023.27652

Source: BioImpacts - February 8, 2024 Category: Research Authors: Duong Thi Thuy Le Cuong Manh Vu Thuy Thi Bich Ly Nam Trung Nguyen Phuong Thi Mai Nguyen Ha Hoang Chu Source Type: research