Proton therapy induces a local microglial neuroimmune response

CONCLUSION: Overall, our data indicate that the brain responds in a similar manner to photons and plateau protons with a shared local upregulation of microglial priming-associated genes, potentially enhancing the immune response to subsequent inflammatory challenges.PMID:38453539 | DOI:10.1016/j.radonc.2024.110117

Source: Radiotherapy and Oncology : journal of the European Society for Therapeutic Radiology and Oncology - March 7, 2024 Category: Radiology Authors: Dani ëlle C Voshart Myrthe Klaver Yuting Jiang Hilmar R J van Weering Fleur van Buuren-Broek Gideon P van der Linden Davide Cinat Harry H Kiewiet Justin Malimban Daniel A Vazquez-Matias Luiza Reali Nazario Ayla C Scholma Jeffrey Sewdihal Marc-Jan van Goe Source Type: research