Impacts of Posttransplant Cyclophosphamide Dose on Graft-versus-leukemia Effects via HLA-B Leader in HLA-haploidentical Peripheral Blood Stem Cell Transplantation

CONCLUSION: Our findings suggest that the effect of the patient HLA-B leader genotype is modified by the PTCy dose, providing immunological insight into the PTCy dosage and supporting further studies to investigate the underlying mechanisms.PMID:38432202 | DOI:10.1159/000538078

Source: Acta Haematologica - March 3, 2024 Category: Hematology Authors: Makoto Moriguchi Kentaro Ido Hiroshi Okamura Mika Nakamae Kazuki Sakatoku Yosuke Makuuchi Masatomo Kuno Teruhito Takakuwa Asao Hirose Mitsutaka Nishimoto Yasuhiro Nakashima Hideo Koh Masayuki Hino Hirohisa Nakamae Source Type: research