Plasmatic profiles of cytokines/chemokines, glial fibrillary acidic protein (GFAP) and MRI brain damage in neonates with hypoxic ischemic encephalopathy (HIE)

CONCLUSION: In a small number of infants with worse brain MRI, we found higher levels of GFAP and of IL-10 at T4 and a trend toward low IL-18 levels than in infants with normal MRI, considered early biomarker of brain damage and a predictor of adverse outcome, respectively. The greatest, although not significant, difference between the levels of molecules was found in cases and controls at time points T2 and T3, during TH.PMID:38442443 | DOI:10.1016/j.cyto.2024.156565

Source: Cytokine - March 5, 2024 Category: Molecular Biology Authors: Cinzia Auriti Vito Mond ì Fiammetta Piersigilli Laura Timelli Tamara Del Pinto Giusi Prencipe Giulia Lucignani Daniela Longo Iliana Bersani Source Type: research