Therapeutic role of miR-26a on cardiaorenal injury in mice model of angiotensin-II induced chronic kidney disease through inhibition of LIMS1/ILK pathway

CONCLUSIONS: Our findings suggest that miR-26a could be a promising therapeutic target for the treatment of cardiorenal injury in CKD. This is attributed to its ability to regulate the LIMS1/ILK signaling pathway, which represents a common molecular mechanism in both heart and kidney tissues.PMID:38445356 | DOI:10.1097/CM9.0000000000002978

Source: Chinese Medical Journal - March 6, 2024 Category: General Medicine Authors: Weijie Ni Yajie Zhao Jinxin Shen Qing Yin Yao Wang Zuolin Li Taotao Tang Yi Wen Yilin Zhang Wei Jiang Liangyunzi Jiang Jinxuan Wei Weihua Gan Aiqing Zhang Xiaoyu Zhou Bin Wang Bi-Cheng Liu Source Type: research