Efficacy and safety of prazequantel for the treatment of < i > Schistosoma mansoni < /i > infection across different transmission settings in Amhara Regional State, northwest Ethiopia

ConclusionsA single dose of 40 mg/kg PZQ was efficacious and safe for the treatment ofS.mansoni infection when it was evaluated by the KK test, but a lower efficacy was recorded when it was evaluated by the POC-CCA test. However, the POC-CCA test ’s specificity, clearance time of CCA from urine after treatment, and interpretation of weakly reactive (trace) test results need further research.
Source: PLoS One - Category: Biomedical Science Authors: Source Type: research