Multi-centers experience using therapeutic plasma exchange for corticosteroid/tocilizumab-refractory cytokine release syndrome following CAR-T therapy

In conclusion, TPE may serve as a valuable and safe adjunct to corticosteroids and tocilizumab in the management of severe CRS resulting from CAR-T cell infusion. We eagerly await further prospective studies to validate this finding.PMID:38422769 | DOI:10.1016/j.intimp.2024.111761

Source: International Immunopharmacology - February 29, 2024 Category: Allergy & Immunology Authors: Yedi Pu Yifan Zhao Yuekun Qi Yang Liu Meng Zhang Xia Xiao Hairong Lyu Juanxia Meng Haibo Zhu Kailin Xu Weidong Han Mingfeng Zhao Source Type: research