Sleep and APOE- ε4 have a synergistic effect on plasma biomarkers and longitudinal cognitive decline in older adults

CONCLUSION: Our study highlights sleep disorder was associated with cognitive decline, with plasma NfL playing a partial mediating role. These findings explain how sleep disorders affect cognitive function and emphasize the importance of healthy sleep for older adults.PMID:38421124 | DOI:10.1111/cns.14558

Source: CNS Neuroscience and Therapeutics - February 29, 2024 Category: Neuroscience Authors: Xianfeng Yu Xia Zhou Zhengbo He Beiqi He Ke Wan Min Wei Tengfei Guo Ying Han Source Type: research