Cardiac damage and tropism of severe acute respiratory syndrome coronavirus 2

Curr Opin Microbiol. 2024 Feb 22;78:102437. doi: 10.1016/j.mib.2024.102437. Online ahead of print.ABSTRACTUntil now, the World Health Organization registered over 771 million cases of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection worldwide, of which 6.97 million resulted in death. Virus-related cardiovascular events and pre-existing heart problems have been identified as major contributing factors to global infection-related morbidity and mortality, emphasizing the necessity for risk assessment and future prevention. In this review, we highlight cardiac manifestations that might arise from an infection with SARS-CoV-2 and provide an overview of known comorbidities that worsen the outcome. Additionally, we aim to summarize the therapeutic strategies proposed to reverse virus-associated myocardial damage, which will be further highlighted in this review, with an outlook to successful recovery and prevention.PMID:38394964 | DOI:10.1016/j.mib.2024.102437
Source: Current Opinion in Microbiology - Category: Microbiology Authors: Source Type: research