Plasma S1P Orchestrates the Reverse Transendothelial Migration of Aortic Intimal Myeloid Cells in Mice

CONCLUSIONS: Functional and expression studies support a novel role for S1P signaling in the regulation of lipopolysaccharide-induced RTM and the homeostatic maintenance of aortic intimal MCs. Our data provide insight into how circulating plasma mediators help orchestrate intimal MC dynamics.PMID:38328936 | DOI:10.1161/ATVBAHA.123.320227

Source: Arteriosclerosis, Thrombosis and Vascular Biology - February 8, 2024 Category: Cardiology Authors: Chanele K Polenz Corey A Scipione Sharon J Hyduk Marwan G Althagafi Hisham M Ibrahim Myron I Cybulsky Source Type: research