The universal effects of low-dose interleukin-2 across 13 autoimmune diseases in a basket clinical trial

CONCLUSION: IL-2LD was well-tolerated, exhibiting specific Treg activation and clinical improvements across the 13 autoimmune diseases.CLINICAL IMPLICATION: Tregs stimulation by IL-2LD is a promising therapeutic strategy and IL-2LD holds considerable promise for integration into combinatorial therapeutic approaches.PMID:38330545 | DOI:10.1016/j.jaut.2024.103172

Source: Journal of Autoimmunity - February 8, 2024 Category: Allergy & Immunology Authors: Roberta Lorenzon Claire Ribet Fabien Pitoiset Selim Aractingi Beatrice Banneville Laurent Beaugerie Francis Berenbaum Patrice Cacoub Julien Champey Olivier Chazouilleres Christophe Corpechot Bruno Fautrel Ars ène Mekinian Elodie Regnier David Saadoun Joe Source Type: research