Comparative In Vitro Study of the Cytotoxic Effects of Doxorubicin's Main Metabolites on Cardiac AC16 Cells Versus the Parent Drug

In conclusion, our findings suggest that metabolism may not be a pivotal factor in mediating DOX's cardiotoxic effects.PMID:38347287 | DOI:10.1007/s12012-024-09829-6

Source: Cardiovascular Toxicology - February 12, 2024 Category: Cardiology Authors: Ana Reis-Mendes Cl áudia Vitorino-Oliveira Mariana Ferreira F élix Carvalho Fernando Remi ão Em ília Sousa Maria de Lourdes Bastos Vera Marisa Costa Source Type: research