Calendar-period trends in cervical precancer and cancer diagnoses since the introduction of human papillomavirus and cytology co-testing into routine cervical cancer screening at Kaiser Permanente Northern California

CONCLUSIONS: Since its introduction at KPNC, co-testing increased the detection of CIN3 over time, which likely caused a subsequent reduction of SCC. However, there has been no observed decrease in ADC. One possible explanation for lack of effectiveness against ADC is the underdiagnosis of AIS. Novel strategies to identify and treat women at high risk of ADC need to be developed and clinically validated.PMID:38301311 | DOI:10.1016/j.ygyno.2024.01.038

Source: Gynecologic Oncology - February 1, 2024 Category: Cancer & Oncology Authors: Brian Befano Nicolas Wentzensen Thomas Lorey Nancy Poitras Li C Cheung Mark Schiffman Megan A Clarke Camryn Cohen Walter Kinney Alex Locke Philip E Castle Source Type: research