Paclitaxel and Carboplatin in Combination with Low-Intensity Pulsed Ultrasound for Glioblastoma

CONCLUSIONS: Combining paclitaxel and carboplatin in gliomas may be more efficacious than monotherapy, as in other cancers, due to synergy and independent susceptibility to each drug. These results form the basis for an ongoing phase II trial (NCT04528680) where we investigate this combination with LIPU/MB.PMID:38295144 | DOI:10.1158/1078-0432.CCR-23-2367

Source: Clinical Cancer Research - January 31, 2024 Category: Cancer & Oncology Authors: Karl J Habashy Crismita Dmello Li Chen Victor A Arrieta Kwang-Soo Kim Andrew Gould Mark W Youngblood Guillaume Bouchoux Kirsten B Bell Burdett Hui Zhang Michael Canney Roger Stupp Adam M Sonabend Source Type: research