Goal-directed fluid therapy guided by plethysmographic variability index versus conventional liberal fluid therapy in neonates undergoing abdominal surgery: A prospective randomized controlled trial

CONCLUSION: Intraoperative plethysmographic variability index-guided goal-directed fluid therapy was comparable to liberal fluid therapy in terms of total volume of fluid infused in neonates during perioperative period. More randomized controlled trials with higher sample size are required.TRIAL REGISTRATION: Central Trial Registry of India (CTRI/2020/02/023561).PMID:38348932 | DOI:10.1111/pan.14856
Source: Paediatric Anaesthesia - Category: Anesthesiology Authors: Source Type: research