Tumor necrosis factor α-induced protein 8-like-2 controls microglia phenotype via metabolic reprogramming in BV2 microglial cells and responses to neuropathic pain

This study reveals that TNFAIP8L2 plays a critical role in neuropathic pain, providing important insights into glucose metabolic reprogramming and microglial phenotypic transition, which indicates that TNFAIP8L2 may be used as a potential drug target for the prevention of neuropathic pain.PMID:38309648 | DOI:10.1016/j.biocel.2024.106541
Source: The International Journal of Biochemistry and Cell Biology - Category: Biochemistry Authors: Source Type: research