Genetic complexity alters drug susceptibility of asexual and gametocyte stages of < em > Plasmodium falciparum < /em > to antimalarial candidates

In conclusion, this is the first study to investigate the efficacy of antimalarial candidates on both ABS parasites and gametocytes from P. falciparum clinical isolates where the influence of parasite genetic complexity is highlighted, ultimately aiding the malaria elimination agenda.PMID:38259087 | DOI:10.1128/aac.01291-23

Source: Antimicrobial Agents and Chemotherapy - January 23, 2024 Category: Microbiology Authors: Nicola Greyling Mari ëtte van der Watt Hazel Gwarinda Ashleigh van Heerden Bryan Greenhouse Didier Leroy Jandeli Niemand Lyn-Mari é Birkholtz Source Type: research