Transition of management strategies and long-term outcomes in cancer-associated venous thromboembolism from the warfarin era to the direct oral anticoagulant era

CONCLUSIONS: In the current historical comparison of cancer-associated VTE between the 2 large real-world registries, there was a striking change in the treatment strategies with decreased risks of recurrent VTE and major bleeding in the DOAC era compared with those in the warfarin era, while there seemed to be unmet needs of DOAC-related gastrointestinal bleeding.CLINICAL TRIAL REGISTRATION: URL: http://www.umin.ac.jp/ctr/index.htm UNIQUE IDENTIFIER: UMIN000044816.PMID:38278660 | DOI:10.1016/j.ejim.2024.01.012

Source: European Journal of Internal Medicine - January 26, 2024 Category: Internal Medicine Authors: Ryuki Chatani Yugo Yamashita Takeshi Morimoto Kazuhisa Kaneda Kazunori Mushiake Kazushige Kadota Yuji Nishimoto Nobutaka Ikeda Yohei Kobayashi Satoshi Ikeda Kitae Kim Moriaki Inoko Toru Takase Shuhei Tsuji Maki Oi Takeshi Kimura COMMAND VTE Registry-2 Inv Source Type: research