Genetic susceptibility for retinopathy of prematurity and its associated comorbidities
CONCLUSION: We identified three maternal and three perinatal risk factors associated with ROP. Genes EPAS1 and AGTR1, involved in angiogenesis and vascularization, were identified to be of risk for ROP.IMPACT: Genetic and environmental risk factors associated with ROP and its comorbidities are evaluated in a Latin American population. Genes EPAS1 and AGTR1, involved in angiogenesis and vascularization, were identified to be of risk for ROP. Three maternal and three perinatal risk factors associated with ROP were also identified. A matrix of significant relationships among genetic markers and comorbidities is presented. Reported data may help develop more effective preventive measures for ROP in the Latin American region.PMID:38347174 | DOI:10.1038/s41390-024-03068-9
Source: Pediatric Research - Category: Pediatrics Authors: Lucas G Gimenez Juan A Gili Dar ío E Elias Rub én Sagula Bel én Comas Mar ía R Santos Hebe Campa ña Fernando A Poletta Silvina L Heisecke Julia Ratowiecki Viviana R Cosentino Roc ío Uranga C ésar Saleme Mercedes Negri M ónica Rittler Jorge Zapata Source Type: research
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