Stop using the misidentified cell line LO2 as a human hepatocyte

Recently, we read the article by Song et  al. in the Journal of Hepatology.1 Using cellular and animal models, the authors concluded that B. pseudolongum protected against non-alcoholic fatty liver disease-associated hepatocellular carcinoma (NAFLD-HCC) by secreting the antitumor metabolite acetate through the gut-liver axis, and thus, s uggested that B. pseudolongum is a potential probiotic for NAFLD-HCC prevention. Undoubtedly, the results of this study are very promising regarding a novel probiotic for the potential prevention and treatment of NAFLD-HCC in humans.
Source: Journal of Hepatology - Category: Gastroenterology Authors: Tags: Letter to the Editor Source Type: research