Measurement of Respiratory System Function By Airwave Oscillometry (AOS) in a Cohort of Children Undergoing Hematopoietic Stem Cell Transplant (HSCT)

Respiratory complications are common following HSCT in children. The most sensitive tests to evaluate these complications are unknown. Airwave oscillometry has been proposed to be a sensitive test of disorders of the mechanics of the respiratory system, including large and small airway dysfunction and elevated respiratory system stiffness due to pulmonary parenchymal or chest wall damage. We performed oscillometry (Tremoflo ã C100, Thorasys, Montreal, CA) at baseline and following HSCT in a cohort of 56 children at 3 of 4 centers to date: Cincinnati Children's Hospital, Children's Hospital of Philadelphia, University of Minnesota Children's Hospital, and Boston Children's Hospital.

Source: Biology of Blood and Marrow Transplantation - February 1, 2024 Category: Hematology Authors: Maureen B. Josephson, Joseph M. McDonough, Lisa R. Young, Jason L. Freedman, Christopher Towe, Eleanor Cook, Jonathan M. Gaffin, Dr. Jane Koo, Margaret L. MacMillan, Kasiani C Myers, Leslie E. Lehmann, Laura L. Walkup, Wai Wong, Jason C. Woods, Stella M. Tags: 161 Source Type: research