Multilocus Genetic Risk Score Associates With Ischemic Stroke in Case-Control and Prospective Cohort Studies [Clinical Sciences]

Conclusions—
A multilocus GRS based on common variants for established cardiovascular risk factors was significantly associated with IS both in clinic-based samples and in the general population. However, the improvement in clinical risk prediction was found to be small.

Source: Stroke - January 27, 2014 Category: Neurology Authors: Malik, R., Bevan, S., Nalls, M. A., Holliday, E. G., Devan, W. J., Cheng, Y.-C., Ibrahim-Verbaas, C. A., Verhaaren, B. F. J., Bis, J. C., Joon, A. Y., de Stefano, A. L., Fornage, M., Psaty, B. M., Ikram, M. A., Launer, L. J., van Duijn, C. M., Sharma, P., Tags: Genetics of Stroke Clinical Sciences Source Type: research