Silencing of secreted phosphoprotein 1 attenuates sciatic nerve injury ‐induced neuropathic pain: Regulating extracellular signal‐regulated kinase and neuroinflammatory signaling pathways

ConclusionsThe data indicate that silencing SPP1 attenuates NP via inactivation of the ERK pathway, suggesting that SPP1 may be a promising target for NP treatment.

Source: Immunity, Inflammation and Disease - February 2, 2024 Category: Allergy & Immunology Authors: Haiyu Xie, Feng Lu, Xiaoling Li, Enfu Wang, Jiao Mo, Weidong Liang Tags: ORIGINAL ARTICLE Source Type: research