Tnf signaling deficiency promotes UVB-induced melanocyte stem cell activation and migration

In recent decades, the incidence rate of melanoma has risen rapidly in the United States ( “Melanoma Skin Cancer Statistics” 2023), with ultraviolet B (UVB) exposure representing a significant risk factor (Armstrong and Kricker 2001). Understanding the cellular and molecular mechanisms of UVB-induced melanocyte stem cell (McSC) activation could uncover novel methods to prevent melanom a initiation.
Source: Journal of Investigative Dermatology - Category: Dermatology Authors: Tags: Letters to the Editor Source Type: research