Bifocal malakoplakia in a patient living with HIV: case report

CONCLUSION: This report presents a distinctive and complex case of malakoplakia in an HIV-positive patient, a rare inflammatory disorder originally described by Michaelis and Gutmann in 1902. The hallmark Michaelis-Gutmann organisms were observed, confirming the diagnosis. While typically affecting the urinary tract, this case demonstrates the exceptional ability of malakoplakia to manifest in various organ systems, including pulmonary, gastrointestinal, and more. Although Escherichia coli is a prevalent associated pathogen, the exact cause remains elusive. Treatment, often involving surgical excision and antibiotic therapy, underscores the challenging nature of managing this condition in immunocompromised individuals.PMID:38185638 | DOI:10.1186/s12981-024-00592-w

Source: AIDS Research and Therapy - January 7, 2024 Category: Infectious Diseases Authors: Mohammed Alsaeed Mohamed Mursi Nazik Eltayeb Hadi Kuriry Salafa Albaghli Yasir Alrusayni Source Type: research