Does the Expanded Controlled Evidence Now Mandate the Routine Use of Machine Perfusion in Kidney Transplantation?

The quality of donor kidneys may be improved by taking therapeutic measures that begin before transplant. A recent large-scale prospective trial from the United States by Malinoski et  al1 reported that machine perfusion (MP) was superior to targeted donor hypothermia in reducing delayed graft function (DGF) after kidney transplant from a brain-dead donor (DBD). Delayed graft function was defined as need for dialysis during the first 7 days after transplant. However, the trial f ound no measurable effect on 1-year graft survival.
Source: Mayo Clinic Proceedings - Category: Internal Medicine Authors: Tags: Perspectives and controversies Source Type: research