Predisposition to atherosclerosis in children and adults with trisomy 21: biochemical and metabolomic studies

CONCLUSIONS: Down syndrome individuals show distinct cardiovascular risks, with decreased HDL and increased LDL levels. Combined with metabolomic disparities and higher BMI and TMI, this suggests an increased atherosclerosis risk compared to controls.PMID:38031830 | PMC:PMC10679913 | DOI:10.5114/pedm.2023.131162

Source: Pediatric Endocrinology, Diabetes, and Metabolism - November 30, 2023 Category: Endocrinology Authors: Marta Hetman Karolina Mielko Sylwia Placzkowska Aleksandra Bodetko Piotr M łynarz Ewa Barg Source Type: research