Immune and oxidative stress biomarkers in pediatric psychosis and psychosis-risk: Meta-analyses and systematic review

CONCLUSION: Results from several studies are consistent with the hypothesis that signals often classified as "proinflammatory" are elevated in threshold pediatric psychotic disorders. Data are less clear for immune markers in subthreshold psychosis and redox markers across the subthreshold and threshold psychosis spectrum. Immune and redox biomarker intervention studies are lacking, and research investigating interventions targeting the immune system in threshold pediatric psychosis is especially warranted.PMID:38141839 | DOI:10.1016/j.bbi.2023.12.019

Source: Brain, Behavior, and Immunity - December 23, 2023 Category: Neurology Authors: Jerome Henry Taylor Julieta Bermudez-Gomez Marina Zhou Oscar Gomez Casey Ganz-Leary Cesar Palacios Zeeshan M Huque Ran Barzilay David R Goldsmith Raquel E Gur Source Type: research