Dietary fibre confers therapeutic effects in a preclinical model of Huntington's disease

In conclusion, high-fibre intake was effective in enhancing gastrointestinal function, cognition and affective behaviors in HD mice. These findings indicate that dietary fibre interventions may have therapeutic potential in Huntington's disease to delay clinical onset, and have implications for related disorders exhibiting dysfunction of the gut-brain axis.PMID:38142919 | DOI:10.1016/j.bbi.2023.12.023

Source: Brain, Behavior, and Immunity - December 24, 2023 Category: Neurology Authors: Carolina Gubert Geraldine Kong Callum Costello Cameron D Adams Bethany A Masson Wendy Qin Jocelyn Choo Vinod K Narayana Geraint Rogers Thibault Renoir John B Furness Anthony J Hannan Source Type: research