sVEGF-R1 in acute non-infectious toxicity syndromes after pediatric allogeneic hematopoietic stem cell transplantation

CONCLUSION: VEGF-R1 levels are found to be increased in pediatric patients developing SOS, reflecting the severity of morbidity. sVEGF-R1 were unassociated with both CLS and ES. The potential of sVEGF-R1 as a clinically useful biomarker for SOS should be further explored to improve pre-transplant SOS-risk assessment, SOS-severity grading, and to guide treatment.PMID:38122992 | DOI:10.1016/j.trim.2023.101975

Source: Transplant Immunology - December 20, 2023 Category: Transplant Surgery Authors: Denise Elb æk Horan Katrine Kielsen Sarah Wegener Weischendorff Maria Ebbesen S ørum Marte B Kammersgaard Marianne Ifversen Claus Nielsen Lars P Ryder P är I Johansson Klaus M üller Source Type: research