Chemokine CCL2 promotes cardiac regeneration and repair in myocardial infarction mice via activation of the JNK/STAT3 axis

In conclusion, this study suggests that CCL2 promotes cardiac regeneration via activation of STAT3 signaling, underscoring its potential as a therapeutic agent for managing MI and associated heart failure.PMID:38086898 | DOI:10.1038/s41401-023-01198-0

Source: Acta Pharmacologica Sinica - December 12, 2023 Category: Drugs & Pharmacology Authors: Wei Wang Xiao-Kang Chen Lu Zhou Feng Wang Yan-Ji He Bing-Jun Lu Ze-Gang Hu Zhu-Xin Li Xue-Wei Xia Wei Eric Wang Chun-Yu Zeng Liang-Peng Li Source Type: research