Long-term Intracranial Outcomes with Combination Dual Immune-Checkpoint Blockade and SRS in Patients with Melanoma and NSCLC Brain Metastases

CONCLUSIONS: The addition of D-ICPI for patients with melanoma and NSCLC undergoing SRS is associated with improved local and intracranial control. This appears to be an effective strategy, including for patients with symptomatic or multiple BMs.PMID:38097090 | DOI:10.1016/j.ijrobp.2023.12.002

Source: Cancer Control - December 14, 2023 Category: Cancer & Oncology Authors: Eugene J Vaios Rachel F Shenker Peter G Hendrickson Zihan Wan Donna Niedzwiecki Sebastian F Winter Helen A Shih Jorg Dietrich Chunhao Wang April K S Salama Jeffrey M Clarke Karen Allen Paul Sperduto Trey Mullikin John P Kirkpatrick Scott R Floyd Zachary J Source Type: research