Allocholic acid protects against α‐naphthylisothiocyanate‐induced cholestasis in mice by ameliorating disordered bile acid homeostasis

In conclusion, ACA demonstrated its potential to ameliorate ANIT-induced liver damage by inhibiting BA synthesis and promoting both BA efflux and renal elimination pathways, thus, restoring BA homeostasis.

Source: Journal of Applied Toxicology - November 16, 2023 Category: Toxicology Authors: Xue Han, Chuyi Lin, Huijie Liu, Shan Li, Bei Hu, Lei Zhang Tags: RESEARCH ARTICLE Source Type: research