Increased Delta and Theta Power Density in Sickle Cell Disease Individuals with Chronic Pain Secondary to Hip Osteonecrosis: A Resting-State Eeg Study

CONCLUSION: This study indicates that individuals with SCD experiencing hip osteonecrosis and chronic pain manifest a dysfunctional EEG pattern characterized by the persistence of low-frequency PSD during a resting state. This dysfunctional EEG pattern may be linked to clinical and biochemical outcomes, including depression symptoms, pain severity during movement, and serum BDNF levels.PMID:38060074 | DOI:10.1007/s10548-023-01027-x

Source: Brain Topography - December 7, 2023 Category: Neuroscience Authors: Tiago S Lopes Jamille E Santana Wellington S Silva Francisco J Fraga Pedro Montoya Katia N S á Larissa C Lopes Rita Lucena Yossi Zana Abrah ão F Baptista Source Type: research