Neurodevelopmental assessment of normocephalic children born to Zika virus exposed and unexposed pregnant people

CONCLUSIONS: This study found no statistically significant differences in the neurodevelopment of normocephalic children between in utero ZIKV exposed and unexposed. Nevertheless, long-term monitoring of children with in utero ZIKV exposure is warranted.IMPACT: This study found no statistically significant differences in the neurodevelopment in normocephalic children with in utero Zika virus exposure compared to unexposed children, although the exposed group showed lower cognitive and language scores that persisted after adjustment by maternal age and education and after excluding children born preterm and low birth weight from the analysis. Children with prenatal Zika virus exposure, including those normocephalic and have no evidence of abnormalities at birth, should be monitored for neurodevelopmental delays. Follow-up is important to be able to detect developmental abnormalities that might not be detected earlier in life.PMID:38057577 | DOI:10.1038/s41390-023-02951-1

Source: Pediatric Research - December 6, 2023 Category: Pediatrics Authors: Jackeline Alger Mar ía Luisa Cafferata Raquel L ópez Lisa D Wiggins Allison Callejas Mario Castillo Jenny F únes F átima Rico Diana Valencia Douglas Varela Zulma Alvarez Mabel Berrueta Harry Bock Carolina Bustillo Alejandra Calder ón Alvaro Ciganda J Source Type: research