Imperatorin interacts additively with novel antiseizure medications in the mouse maximal electroshock-induced seizure model: an isobolographic transformation

CONCLUSIONS: The additive interactions of IMP with LCM, OXC, PGB, and TPM in the mouse MES model accompanied by no pharmacokinetic changes in the total brain content of ASMs are worthy of recommendation for further studies.PMID:38015370 | DOI:10.1007/s43440-023-00555-4

Source: Pharmacological Reports - November 28, 2023 Category: Drugs & Pharmacology Authors: Jarogniew J Łuszczki Ewelina Kochman-Moskal Hubert Bojar Magdalena Florek- Łuszczki Krystyna Skalicka-Wo źniak Source Type: research