What is pregabalin and why can it be dangerous?
The prescription drug has been linked to a number of deaths in the UK and around the world. (Source: BBC News | Health | UK Edition)
Source: BBC News | Health | UK Edition - March 21, 2024 Category: Consumer Health News Source Type: news

Inside the UK's battle with pregabalin: How addiction fears over opioids and benzos left country sleepwalking towards unfolding fiasco with 'Valium on steroids' - as map reveals areas where up to one in 25 residents are given powerful anti-anxiety pills
Tens of thousands of Brits take the prescription-only drug, nicknamed 'Valium on steroids' and the 'new Xanax' by doctors aware of its powerful effects. (Source: the Mail online | Health)
Source: the Mail online | Health - March 4, 2024 Category: Consumer Health News Source Type: news

Pregabalin use in forensic hospitals and prisons in German speaking countries-a survey study of physicians - Novotny M, Bulla J, Hubl D, Fischer SKM, Grosshans M, Gutzeit A, Bilke-Hentsch O, Seifritz E, Mutschler J.
BACKGROUND: Pregabalin is a gamma-aminobutyric acid (GABA) analog that was approved in the EU in 2004 for the treatment of neuropathic pain, generalized anxiety disorder and epilepsy. Since its introduction, pregabalin abuse and misuse has increased signif... (Source: SafetyLit)
Source: SafetyLit - January 26, 2024 Category: International Medicine & Public Health Tags: Alcohol and Other Drugs Source Type: news

Gabapentinoid Use Continues to Climb
(MedPage Today) -- Gabapentinoid users increased from 4.0% in 2015 to 4.7% in 2021, Medical Expenditure Panel Survey (MEPS) data showed. Moreover, gabapentinoids -- which includes gabapentin and pregabalin -- continued to be used for chronic... (Source: MedPage Today Neurology)
Source: MedPage Today Neurology - January 22, 2024 Category: Neurology Source Type: news

Review of the demographic factors and toxicology related to deaths due to pregabalin in Northern Ireland - Huddleston WR, Robert Lyness J, Quinn A.
The potential for recreational abuse of the analgesic and antiepileptic drug pregabalin is now well established in the literature. The potential minimum lethal dose in post mortem cases is however less defined. All post mortem examinations in Northern Irel... (Source: SafetyLit)
Source: SafetyLit - December 18, 2023 Category: International Medicine & Public Health Tags: Alcohol and Other Drugs Source Type: news

Two painkillers Tapentadol and Pregabalin may go off OTC over misuse
The Drugs Controller General of India (DCGI) is considering banning over-the-counter (OTC) sales of pain relievers Tapentadol and Pregabalin to curb misuse. Pregabalin is prescribed for neuropathic pain and fibromyalgia, while Tapentadol is used for seizures. The DCGI has constituted a sub-committee to review the matter, including experts from the regulator's office, clinicians, and pharmacologists. (Source: The Economic Times Healthcare and Biotech News)
Source: The Economic Times Healthcare and Biotech News - November 24, 2023 Category: Pharmaceuticals Source Type: news

Patients with fibromyalgia left in agony due to 'cruel' ban on drugs by NHS chiefs to treat the chronic pain condition whose sufferers include Lady Gaga
Fibromyalgia patients - who endure body-wide pain, muscle stiffness and headaches - had been offered powerful painkillers, including pregabalin and tramadol, until guidelines changed. (Source: the Mail online | Health)
Source: the Mail online | Health - September 23, 2023 Category: Consumer Health News Source Type: news

Pregabalin: Bereaved mother warns of drug abuse dangers
Pauline Duddy's 21-year-old daughter, Jasmin, died with pregabalin in her system in February. (Source: BBC News | Health | UK Edition)
Source: BBC News | Health | UK Edition - August 22, 2023 Category: Consumer Health News Source Type: news

Britney Spears Breaks Silence Amid Sam Asghari Divorce: ‘I Couldn’t Take the Pain Anymore’
Britney Spears is opening up following her split from Sam Asghari. On Friday night (Aug. 18), the 41-year-old pop superstar took to Instagram to break her silence after the fitness instructor and actor, 29, filed for divorce earlier in the week. Related Pink Changes ‘Don’t Let Me Get Me’ Lyric…#britneyspears #samasghari #amidsam #janetjackson #billboard #spears #instagramstories #mariariverred (Source: Reuters: Health)
Source: Reuters: Health - August 19, 2023 Category: Consumer Health News Source Type: news

Proteins Predict Dementia; Brain Function in Long COVID; Pregabalin Plus Opioids
(MedPage Today) -- Plasma analysis in middle-age adults identified protein markers of dementia risk in later life. (Science Translational Medicine) A muscle-building supplement known as beta-hydroxy beta-methylbutyrate (HMB) improved spatial learning... (Source: MedPage Today Neurology)
Source: MedPage Today Neurology - July 26, 2023 Category: Neurology Source Type: news

Positive Results for Cannabis-Based Med for Nerve Pain Positive Results for Cannabis-Based Med for Nerve Pain
Zelira Therapeutics ' cannabinoid-based drug may be a safe, effective, and well-tolerated alternative to pregabalin for diabetic neuropathy, the company said.Medscape Medical News (Source: Medscape Diabetes Headlines)
Source: Medscape Diabetes Headlines - June 1, 2023 Category: Endocrinology Tags: Neurology & Neurosurgery News Source Type: news

Rise of pregabalin poisoning and abuse cases in Serbia: a ten-year retrospective study - Antunovi ć M, Vucinić S, Kotur-Stevuljevic J, Krstic K, Jović-Stošić J, Kilibarda V, Perković-Vukčević N, Djordjević S.
PURPOSE: The aim of this study was to analyze data on gabapentinoid-related attendances to the National Poison Control Center of Serbia (NPCC), particularly abuse cases; to estimate its changes and to compare it with trends in national consumption rates of... (Source: SafetyLit)
Source: SafetyLit - April 19, 2023 Category: International Medicine & Public Health Tags: Alcohol and Other Drugs Source Type: news

Combination therapy for painful diabetic neuropathy is safe and effective
This study (a randomised controlled trial) compared the effectiveness of pregabalin, amitriptyline, and duloxetine. It showed that combinations of these drugs were safe, and equally effective at relieving pain. Clinicians can be reassured that patients can be started on any one of the 3 medications and have another added, if needed. They could discuss the side effects associated with each medication and ask the patient which they would prefer. (Source: Current Awareness Service for Health (CASH))
Source: Current Awareness Service for Health (CASH) - April 6, 2023 Category: Consumer Health News Source Type: news

The US Supreme Court asks the Biden administration to weigh in on lyrics website Genius' attempt to revive a lawsuit over Google's alleged theft of its work
Summary - Companies - Law firms - Related documents - Genius' breach case against Google dismissed based on copyright law - Lyric site said decision could give big tech free pass to copy content (Reuters) - The U.S. Supreme Court on Monday asked the Biden administration to weigh in on song-lyric…#rapgenius #joshuarosenkranz #copyrightacts #mlgeniusholdings #2ndcircuit #reddit #ebay #lyricfind #uscircuitcourtofappeals #googlellc (Source: Reuters: Health)
Source: Reuters: Health - December 14, 2022 Category: Consumer Health News Source Type: news

Review finds little evidence to support gabapentinoid use in bipolar disorder or insomnia
The drugs gabapentin and pregabalin are sometimes prescribed for people with bipolar disorder or insomnia. Research found little evidence that they are effective. The drugs have side effects and can be addictive; the team calls for further trials. Gabapentin and pregabalin (collectively known as gabapentinoids) are licensed in the UK to treat pain and seizures. Pregabalin is also approved for generalised anxiety disorder (when people feel constantly anxious). Both drugs can have side effects, such as drowsiness, dry mouth, dizziness, headache, fatigue and visual disturbance. They can also be addictive. At least half of g...
Source: Current Awareness Service for Health (CASH) - October 24, 2022 Category: Consumer Health News Source Type: news