E670G PCSK9 polymorphism in HeFH & amp; CAD with diabetes: is the bridge to personalized therapy within reach?

CONCLUSION: T2DM in patients with CAD, both with HeFH and non-HeFH, in the Uzbek population was significantly more often associated with the presence of the "gain-of-function" G allele of the PCSK9 E670G genetic polymorphism.PMID:38028979 | PMC:PMC10646404 | DOI:10.3389/fcdhc.2023.1277288

Source: Atherosclerosis - November 29, 2023 Category: Cardiology Authors: Rano Alieva Aleksandr Shek Alisher Abdullaev Khurshid Fozilov Shovkat Khoshimov Guzal Abdullaeva Dariya Zakirova Rano Kurbanova Lilia Kan Andrey Kim Source Type: research