Association of hippocampal subfield volumes with prevalence, course and incidence of depressive symptoms: The Maastricht Study

CONCLUSIONS: Differences in hippocampal fissure, molecular layer and CA volumes might co-occur or follow the onset of depressive symptoms, in particular with a chronic course. Smaller HATA was associated with an increased risk of incident (chronic) depression. Our results could capture a biological foundation for the development of chronic depressive symptoms, and stresses the need to discriminate subtypes of depression to unravel its biological underpinnings.PMID:37993980 | DOI:10.1192/bjp.2023.143

Source: The British Journal of Psychiatry for Mental Science - November 23, 2023 Category: Psychiatry Authors: Jennifer Monereo-S ánchez Jacobus F A Jansen Martin P J van Boxtel Walter H Backes Sebastian K öhler Coen D A Stehouwer David E J Linden Miranda T Schram Source Type: research