Unique Attributes of Guinea Pigs as New Models to Study Ocular Herpes Pathophysiology and Recurrence
CONCLUSIONS: This study demonstrates the potential suitability of guinea pigs as new models for ocular HSV-1 investigations, filling a critical preclinical void of models capable of showcasing spontaneous HSV reactivation in the eye. The observed similarities and differences in the reactions of guinea pigs and rabbits to HSV-1 infection and treatments provide crucial insights, laying the foundation for future studies on ocular HSV pathogenesis, latency, and improved treatment options.PMID:38015175 | DOI:10.1167/iovs.64.14.41
Source: Herpes - Category: Infectious Diseases Authors: Tejabhiram Yadavalli Chandrashekhar Patil Pankaj Sharma Ipsita Volety Hemant Borase Divya Kapoor Deepak Shukla Source Type: research
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