Astaxanthin alleviates PM < sub > 2.5 < /sub > -induced cardiomyocyte injury via inhibiting ferroptosis

CONCLUSIONS: Our study suggest that ferroptosis plays a significant role in the pathogenesis of cardiomyocyte injury induced by PM2.5. AST may serve as a potential therapeutic agent for mitigating cardiomyocyte injury caused by PM2.5 through the inhibition of ferroptosis.PMID:38007415 | PMC:PMC10675963 | DOI:10.1186/s11658-023-00513-1

Source: Cellular and Molecular Biology Letters - November 25, 2023 Category: Biochemistry Authors: Jingyi Ren Bowen Yin Zihao Guo Xiaoya Sun Huanting Pei Rui Wen Ziyi Wang Siqi Zhu Jinshi Zuo Yadong Zhang Yuxia Ma Source Type: research